Figure 1.
Correlation of expression profiles of ncRNAs with protein-coding gene markers during EB differentiation. Genes with well-characterized roles in EB differentiation (A) were used to identify ncRNAs with correlated expression profiles (Pearson’s coefficient > 0.9) in pluripotency (B; red lines; Sox2, Pou5f1), primitive streak formation (C; green lines; Evx1, T), and mesoderm differentiation along the hematopoietic lineage (D; Hba-a1, Hba-x). Expression was detected by microarray from 11 RNA samples isolated from differentiating EBs over a 16-d period.
