Confounding between recombination and selection, and the Ped/Pop method for detecting selection

Click on image to view larger version.

Table 1.

Chromosome and physical position (Mb) of 25 selection candidate regions identified by the HapMap (H) and Chimpanzee (C) consortia, and empirical quantile of recombination rate

Click on table to view larger version.

Table 1.

aThe percentile of the pedigree-based recombination rate in the region, relative to the genome-wide distribution for intervals of the same size.

bAutosomal region showing no evidence of recombination in the pedigree data; these represent 11.2% of all 0.5-Mb regions, and are assigned a percentile of 5.6.

cThe LCT locus is at 136.3 Mb.

dX chromosome region showing no evidence for recombination in the pedigree data.

This Article

  1. Genome Res. 18: 1304-1313

Preprint Server