Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

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Figure 3.
Figure 3.

Allele-specific expression in murine ES and TS cells. Sequence analysis of RT-PCR was used to investigate the allele-specific expression of genes within the Peg10 domain in undifferentiated C57BL/6J (B6) × M. mus castaneus (CAST) ES and TS cells. Both Peg10 and Sgce were paternally expressed (Pat) in both ES and TS cells, whereas Tfpi2 and Asb4 were maternally expressed (Mat) in ES and TS cells. Ppp1r9a and Pon2 show biallelic expression in both cell types. Pon3 expression could not be detected in either cell type.

This Article

  1. Genome Res. 18: 1270-1281

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