Transcription factor and microRNA motif discovery: The Amadeus platform and a compendium of metazoan target sets

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Figure 5.
Figure 5.

Genome-wide chromosomal preference analysis of C. elegans promoters. (A) Screenshot of Amadeus output, showing the top-scoring motif found in the analysis. The motif is highly overrepresented on chromosome IV (P = 8 × 10−63). (B) The motif reported by Ruby et al. (2006), found upstream of many 21U-RNAs, is nearly identical to the one identified de novo by Amadeus.

This Article

  1. Published in Advance April 14, 2008, doi: 10.1101/gr.076117.108 Genome Res. 18: 1180-1189

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