Figure 5.
Chromosome breakpoints (arrows) and disrupted genes. (A) Patient 1: Breakpoint on chromosome 7 maps between the 3′ ends of NOM1 and MNX1 (formerly known as HLXB9); breakpoint on chromosome 9 disrupts the 5′ end of a splicing isoform (accession no. AL136545) of TRPM3. (B) Patient 2: Breakpoint on chromosome 4 disrupts EPHA5; no known genes are in the vicinity of the breakpoint on chromosome 5. (C) Patient 3: Breakpoint on chromosome 12 disrupts MAGT4C; no known genes are close to the breakpoint on chromosome 2.
