Cross-species comparison of important immune-related genes
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aIn vertebrate, IL-1 receptors share the same set of TIR adapters with Toll-like receptors.
bPossible novel recognition receptors.
cSimilar to plant TIR domain.
dSimilar to bacterial TIR domain.
eDFD can be present or absent.
fEstimated to be less than 300–600 genes based on the analysis of trace archives.
gThe first number refers to the gene number or model number; the second number refers to the domain number. 104 refers to those small CTL with carbohydrate-binding motifs (Hibino et al. 2006); 346 refers to the total domain number in the genome.
hRefers to vertebrate DEATH domain adapters TRADD, FADD, CRADD, DEDD, LRDD, MADD.
NES, no evidence (EST, cDNA, homologs in other species, etc.) support.
