Genomic analysis of the immune gene repertoire of amphioxus reveals extraordinary innate complexity and diversity

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Figure 4.
Figure 4.

A schematic of the evolution of the complement system. (Solid line) The pathway has experimental evidence; (dashed lines) no experimental support; (?) the existence of the item or pathway is not verified; (*) amphiMASP1/3 gene can produce two proteins, MASP1 and MASP3; (**) amphioxus contains the most abundant CCP domains, see Supplemental Table S1; (***) the human C1q proteins recognize antibody, while the lamprey C1q serves as a lectin.

This Article

  1. Published in Advance June 18, 2008, doi: 10.1101/gr.069674.107 Genome Res. 18: 1112-1126

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