The amphioxus genome illuminates vertebrate origins and cephalochordate biology

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Figure 2.
Figure 2.

The amphioxus genome contains 15 Hox genes. (A) Genomic organization of the 470-kb amphioxus Hox gene cluster and linked Evx gene pair; beneath the horizontal line are shown the two Hox15 cosmid clones analyzed. Black vertical lines represent small sequence gaps; asterisks indicate genes with an intron within the homeobox; arrows denote transcriptional orientation. FISH to amphioxus interphase nucleus (B) and metaphase chromosomes (C–E). (Red signal) Cosmid MPMGc117I2469 (AmphiHox15); (green signal) cosmid MPMGc117L0856 (AmphiHox12 and AmphiHox13). Methods as described in Castro and Holland (2002).

This Article

  1. Published in Advance June 18, 2008, doi: 10.1101/gr.073676.107 Genome Res. 18: 1100-1111

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