Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition

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Figure 4.
Figure 4.

Polymorphic L1s are bona fide products of recent retrotransposition. The length distribution of (A) polymorphic L1s (absent from at least one of the unassembled strains), (B) nonpolymorphic L1s (present in all five strains), and (C) reference L1s (present in the C57 genome) is presented for elements with both a poly(A) tail and TSD (white), TSD alone (light gray), or neither (black). Polymorphic L1s are much more likely to be full length and to have both a poly(A) tail and TSD. See Supplemental Figure 3 and Supplemental Table 6.

This Article

  1. Genome Res. 18: 869-880

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