Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: Implication for retrotransposon-mediated genome evolution

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 8.
Figure 8.

Model for possible role of nonautonomous type IAP protein. (A) IAP particle formation mediated by IΔ1 type IAP protein. Transcript of IΔ1 type IAP element is bound by IΔ1 type IAP protein immediately after translation. The full-length type autonomous IAP protein is recruited to the RNA–protein complex through interaction between IΔ1 type and full-length type IAP proteins, leading to the formation of transposition competent IAP particle. (B) Inefficient formation of IAP particle in the absence of IΔ1 type IAP protein. Accessibility of full-length type autonomous IAP protein to IΔ1 type IAP transcript is impaired due to the lack of IΔ1 type IAP protein. Note that the conformation of the IΔ1 type IAP protein in the IAP particle is unknown and only schematically drawn here.

This Article

  1. Genome Res. 18: 859-868

Preprint Server