Figure 4.
Analysis of reciprocal expression of microRNAs and computationally predicted targets. (A) Proportions of reciprocally expressed or coexpressed microRNA and protein pairs, or pairs of randomly selected microRNAs and differentially expressed proteins, that matched computational prediction using the indicated algorithm are shown. Details of the calculation are described in Methods. (*) P < 0.05 (Z-test). (B) Anti-miR-450 and pre-miR-450 (50 nM) significantly increased and decreased, respectively, the protein expression level of HNRPK in HK-2 cells. n = 4; (*) P < 0.05 vs. control.
