Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

H3ac profile around TSSs. H3ac profiles around TSS of PCGs (A), human mRNAs (B), and spliced ESTs (C) depending on the presence/absence of CpG islands. All genes are bound by H3ac within 1 kb of their TSSs. H3ac binding profiles were created for each group by plotting the H3ac ChIP-chip binding signals (in log2 scale, Y-axes) around the TSS of each transcript, using a window of ±2 kb (X-axes, positive numbers are downstream of TSS; negative numbers are upstream of TSS).

This Article

  1. Genome Res. 18: 380-392

Preprint Server