Uncertainty in homology inferences: Assessing and improving genomic sequence alignment

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Figure 6.
Figure 6.

Dependence of alignment accuracy on modeling fidelity and inference procedure. Shown are the sensitivity, false-positive fraction, and nonhomologous fraction for three inference algorithms and various alignment models (see Table 1) used to align sequences from the human–mouse evolutionary simulation.

This Article

  1. Genome Res. 18: 298-309

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