Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b

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Figure 4.
Figure 4.

Implementation and comparison of multiple sequence alignment strategies. Predictions made by AVID, MLAGAN, SLAGAN, phastCons, PipMaker, and WebMCS were compared with functional data generated in this study and with each other. Some analyses were predicated on comparisons using † zebrafish versus fugu comparisons, ‡ zebrafish versus human comparisons as described in the text. Results of these analyses are displayed as custom tracks on the UCSC Genome Browser (genome.ucsc.edu).

This Article

  1. Genome Res. 18: 252-260

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