
Figure 2.
Exons containing extreme BMI SNPs exhibit weak splice sites. Splice acceptor (dark gray) and donor (light gray) site strengths were calculated based on the algorithm by Shapiro and Senapathy (1987) (Y-axis) for constitutive exons (C), alternative exons (A), and exons that harbor synonymous (S) and nonsynonymous (NS) extreme BMI SNPs (X-axis).











