Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

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Figure 4.
Figure 4.

Spatial miRNA promoter activity. (A) Percentage of miRNA promoters that drive expression in a survey of tissues. (B) Multiple miRNA promoters drive expression in various parts of the somatic gonad, including gonadal sheath, vulva, and uterus. (Top) DIC images; (bottom) GFP fluorescence. (C) Multiple miRNA promoters drive GFP expression in the nervous system. (Top) DIC images; (bottom) GFP fluorescence. Additional images can be found in the EDGEdb database (Barrasa et al. 2007). (D) Most miRNAs as well as TFs and “all genes” promoters confer GFP expression in a tissue-specific manner.

This Article

  1. Genome Res. 18: 2005-2015

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