Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 7.
Figure 7.

Performance of co-complex/pathway membership prediction by three diffusion kernels, congruence score, and the raw counts of length-2 paths. Complex data are obtained from the MIPS protein complex database (Mewes et al. 2004). The optimal diffusion parameters used are γ = 0.25 for G+, γ = 0.1 for G and γ = 0.05 for G. (CS) Congruence score; (A2) raw counts of length-2 paths. (A) Precision-recall curves. (B) Receiver operating characteristic curves.

This Article

  1. Genome Res. 18: 1991-2004

Preprint Server