Finding friends and enemies in an enemies-only network: A graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3.
Figure 3.

Performance of predicting genetic interactions from BioGRID by three diffusion kernels and the raw counts of length-3 paths. The optimal diffusion parameters used are γ = 32 for G, γ = 1 for G and γ = 32 for G+. The raw counts of length-3 paths is A3. The odd-parity diffusion kernel G significantly outperforms all other methods. (A) Precision-recall curves. (B) Receiver operating characteristic curves.

This Article

  1. Genome Res. 18: 1991-2004

Preprint Server