Multigenome DNA sequence conservation identifies Hox cis-regulatory elements

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Figure 5.
Figure 5.

Mutating a conserved window in N7 knocked out expression. Element N7 (592 bp) normally drives expression in the posterior bodywall muscle (A). (B) When the 20-bp MUSSA match was reversed, all expression in the posterior bodywall muscle was abolished. Scale bars,10 microns.

This Article

  1. Published in Advance November 3, 2008, doi: 10.1101/gr.085472.108 Genome Res. 18: 1955-1968

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