In-depth characterization of the microRNA transcriptome in a leukemia progression model

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Figure 5.
Figure 5.

Dek-3′ UTR luciferase assays for miR-23a and miR-155. (A) Bar diagram demonstrating the binding of miR-23a and miR-155 to the 3′ UTR of the Dek oncogene. Dek23 comprises only binding sites for miR-23a, whereas Dek155 exhibits only predicted binding sites for miR-155. A nonbinding miRNA was used as negative control. *P < 0.05. (B) Schematic representation of the Dek 3′ UTR constructs and the predicted miRNA binding sites.

This Article

  1. Genome Res. 18: 1787-1797

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