E2F in vivo binding specificity: Comparison of consensus versus nonconsensus binding sites

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Figure 3.
Figure 3.

Characterization of unbound E2F consensus motifs in ENCODE regions. (A) The overlap of the 116 experimentally determined E2F4 sites and the 507 consensus E2F motifs in the ENCODE regions are shown. (B) The percentage of occupied vs. unoccupied consensus E2F motifs that are located within 2 kb of the start site of a known gene are shown. (C) Shown are the percentages of unoccupied E2F consensus motifs in the ENCODE regions that are within the regions identified to be bound by H3me3K27, H3me3K9, and 5-MeC. (D) Shown is a region of chromosome 19, along with the binding pattern of E2F4, H3me3K27, H3me3K9, and 5-MeC and the location of the consensus E2F motifs and start codons.

This Article

  1. Published in Advance October 3, 2008, doi: 10.1101/gr.080622.108 Genome Res. 18: 1763-1777

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