Dispensability of mammalian DNA

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Figure 1.
Figure 1.

Indispensability of mammalian DNA under purifying selection. (A,B) Abundance of primate-dog, rodent-dog nonexonic DNA, respectively. (C,D) Suggested decomposition of above curves. Color scheme after Waterston et al. (2002). (E) Fraction of primate-dog nonexonic DNA lost in rodents, where ultraconserved-like elements are over 300-fold more indispensable than neutral DNA. (F) Fraction of rodent-dog nonexonic DNA lost in primates.

This Article

  1. Published in Advance October 2, 2008, doi: 10.1101/gr.080184.108 Genome Res. 18: 1743-1751

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