Unexpected complexity at breakpoint junctions in phenotypically normal individuals and mechanisms involved in generating balanced translocations t(1;22)(p36;q13)

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Table 1.

Locations of sequences around translocation breakpoints, relative to normal chromosome

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Table 1.

For each derivative (Der1 or Der22) in each subject, we list the original chromosome coordinates from which it most likely arose. Normal chromosome coordinates are given relative to the NCBI March 2006 assembly (except for the chromosome 1 sequence indicated by an asterisk [*], which is relative to the NW_927826 contig from the Celera sequence assembly). Derivative coordinates are relative to the sequences that we obtained around breakpoints. For example, nucleotides 1–169 of the region we sequenced around the derivative 22 breakpoint of subject 13 align 100% identically to positions 9960675–9960843 bp of the positive strand of chromosome 1.

This Article

  1. Genome Res. 18: 1733-1742

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