Array CGH of the S. cerevisiae and S. bayanus genome portions of 17 S. pastorianus strains. (A) Array CGH of the S. cerevisiae genomes. Array CGH data for the S. cerevisiae chromosomes of the S. pastorianus strains are shown in numerical order with chromosome I at the top and chromosome XVI at the bottom. Regions that are strongly green represent loss of that portion of the S. cerevisiae genome; regions that are strongly red represent regions of the S. cerevisiae genome that are amplified; and regions that are neither strongly green nor strongly red have a normal complement of the S. cerevisiae genomic content for that region. (B) Array CGH of the S. bayanus genomes. Array CGH data for the S. bayanus chromosomes of the examined strains are shown in a manner identical to that described in A; note that the three pairs of S. bayanus chromosomes that have experienced reciprocal translocations relative to the S. cerevisiae genome are shown as they exist in S. bayanus, that is, in their translocated form. For these six chromosomes, the translocation breakpoint is shown (for GSY509 only, but are the same for all strains) as a blue vertical line. In every case for the translocated chromosomes, the number of the chromosome is such that the chromosome to the left of the breakpoint is listed first in the name (e.g., chromosome 2-4 has the chromosome homologous to the S. cerevisiae chromosome II to the left side of the blue vertical line, and has the homologous chromosome IV to the right side of the vertical line). For the translocated chromosomes, centromeres are shown as shorter black vertical lines; for all nontranslocated chromosomes, the centromeres are in the same location as for the S. cerevisiae chromosomes in A.
