Figure 2.
The D4Z4 minimal enhancer up-regulates transcription from the FRG1 promoter. The effect of various promoter/enhancer combinations was observed 48 h after transfection. The luciferase activity is shown relative to that obtained with the pGL3 promoter plasmid carrying the SV40 promoter. The SV40 and FRG1 gene promoters are shown as plain and streaked gray ovals, respectively. The SV40 and D4Z4 enhancers are represented with a diamond and triangle, respectively. Luc stands for luciferase reporter gene.
