Whole proteome analysis of post-translational modifications: Applications of mass-spectrometry for proteogenomic annotation

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Figure 12.
Figure 12.

(A) Venn diagram of all signal peptide predictions on confirmed proteins. A total of 94 signal peptide cleavage sites are validated by mass spectrometry (23 of them missed by both SignalP and PrediSi). (B) Number of signal predictions by SignalP (89) and PrediSi (38) rejected due to the observation of peptides upstream of the signal cleavage site. Eight of these sites were predicted by both tools.

This Article

  1. Published in Advance August 9, 2007, doi: 10.1101/gr.6427907 Genome Res. 17: 1362-1377

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