Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure

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Figure 6.
Figure 6.

VSG families. Pairwise comparison within N-terminal domain types. Peptide sequences encoded by 361 type nA VSGs were all scored against each other in ClustalW multiple sequence alignment, and 345 type nB VSGs were compared in the same way (bottom chart). The number of families (left scale of Y-axis) of given size (X-axis) are depicted in black, and the percentage of genes (right scale of Y-axis) within each domain type is depicted in white. VR indicates the family of VSG-related genes.

This Article

  1. Genome Res. 17: 1344-1352

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