PIPSL was under positive selection in the primate ancestor
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aA Fisher’s exact test was used to test the null hypothesis of equal rates of synonymous and nonsynonymous changes on the ancestral PIPSL branch.
bThe values n, s, N, and S were computed by the modified Nei-Gojobori (NG) method (Zhang et al. 1998).
cMore conservative estimates by the original NG method are in parentheses.
dA Fisher’s exact test was used to test the hypothesis of positive selection followed by purifying selection (episodic evolution); the null hypothesis predicts equal rate ratios of n/s between the ancestral branch and descendant lineages.
