Transcription factor modularity in a gene-centered C. elegans core neuronal protein–DNA interaction network

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Figure 2.
Figure 2.

The core neuronal PDI network is enriched for paired homeodomains. The percentage of the different DNA-binding domains in TFs retrieved in the core neuronal PDI network versus all C. elegans TFs. The network is significantly enriched for TFs that possess a homeodomain (HD, P < 0.001), particularly paired homeodomains (HD-PRD, inset, P < 0.001), and is significantly depleted for nuclear hormone receptors (ZF-NHR, P < 0.001).

This Article

  1. Published in Advance May 18, 2007, doi: 10.1101/gr.6148107 Genome Res. 17: 1061-1071

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