Differing patterns of selection in alternative and constitutive splice sites

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Ratio of observed number of changes to neutral expectation in mouse and rat splice sites, by effect on score. Alternative (ALT) sites show lower obs/exp ratio (higher conservation) than constitutive (CONS) sites, for both positive and negative score changes at all positions.

This Article

  1. Genome Res. 17: 1015-1022

Preprint Server