Pan-S replication patterns and chromosomal domains defined by genome-tiling arrays of ENCODE genomic areas

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Figure 7.
Figure 7.

Both active and repressive chromatin marks are present in a pan-S segment. (A) UCSC Genome Browser display of a 500-kb region from Chromosome 13 (ENr132). This Browser picture highlights three tracks: (I) Primers: ChIP-PCR primers (132HM1–3, left to right) to study histone modifications and HP1α-binding sites; (II) RefSeq: positions of all the genes in this chromosomal segment; and (III) the temporal segregation of replication data. (B,C) ChIP-PCR assay across ENr132 region (see Supplemental Table 3 for primers) against methylated histones (H3 Lys4 and H3 Lys9) and HP1α (as indicated).

This Article

  1. Genome Res. 17: 865-876

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