Figure 3.
The distribution of Pearson correlation coefficients for (A) randomly paired genes of unidirectional promoters, (B) randomly paired divergent genes of different bidirectional promoters, and (C) divergent gene pairs of the same bidirectional promoters. Divergent genes from the same bidirectional promoters are more correlated in expression than randomly paired genes of unidirectional promoters (P = 2.2 × 10−16 by the Wilcoxon rank sum test) and randomly paired genes of different bidirectional promoters (P = 1.21 × 10−11).
