Phylogenetic tree relating the set of analyzed species. The depicted topology and branch lengths illustrate the relationships among the analyzed species’ sequences. Analytical support for the represented tree is provided elsewhere (Nikolaev et al. 2007). The numbers next to each species name indicate the amount of sequence (in Mb) examined in this study (some species have >30 Mb of sequence either as a result of lineage-specific expansions of these regions or the resolution with which orthologous sequences can be identified before alignment) (see Supplemental Material for additional details); (red numbers) BAC-derived sequence sequenced to “comparative grade” (see Methods); (blue numbers) sequence obtained from whole-genome sequencing efforts; and (black numbers) finished human sequence. Blue and green branches distinguish mammalian from non-mammalian sequences, respectively.
