Figure 2.
Frequency distributions of posterior probabilities for simulated coding and noncoding sequences. (A) Distribution of posterior probability (pp) of sequences resembling noncoding sequence (NCDS). Ten-thousand random sequences were generated based on the hexamer and pentamer frequencies of intronic ORFs. The great majority of simulated sequences have very small pp, and only 5% of the pp values are >0.2239. (B) The pp distribution of sequences resembling coding sequences (CDSs). Random sequences were generated according to cDNA CDSs. Approximately 10% of the CDS-like random sequences have pp values <0.2239.
