
Ancestral population size estimated from 22 autosomes of the CEU (A) and YRI (B) data (Method 1). For each chromosome and for each SNP recombination distance bin (0.001 cM spacing), Ne was estimated from the mean r2, using E(r2) = 1/(α + 4Nec). The number of generations in the past was calculated as 1/(2c), and was truncated at 5000. Effective population size has increased dramatically in the last ∼1000 generations (20,000 yr), from a fairly constant ancestral size of ∼2500 (CEU) and ∼7000 (YRI).











