Figure 5.
(A) L1MB5 insertion in an intron of the OTC gene. The upper gel image shows PCR products obtained by amplifying different mammalian genomic DNAs with conserved primers flanking the retroposon insertion site. Below is a partial alignment of the exonic (underlined)/intronic sequences flanking the L1MB5 insertion from 26 placental mammals. The central portion of the inserted sequence has been edited, as shown by the double slash marks. (B) A multispecies alignment showing the second L1MB5 insertion in an intron of the RABGAP1L gene from 23 placental mammals. Direct repeats are highlighted in gray.
