Improving gene annotation using peptide mass spectrometry

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Figure 3.
Figure 3.

A portion of the exon graph for heterogeneous nuclear ribonuclear protein K. The labeled edge represents a codon split across a splice junction. The dotted edge is an “adjacent edge” corresponding to a longer form of an exon. Searching the exon graph reveals peptides spanning both outgoing edges from the central node, confirming alternative splicing at the level of translation.

This Article

  1. Genome Res. 17: 231-239

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