Targeted discovery of novel human exons by comparative genomics

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Gene predictions, cDNA evidence, and novel gene fragments in the region on chromosome 1 that includes ngf51ngf55. Gene predictions are shown in green, prior cDNA evidence is in black, RSTs (which are represented in GenBank as ESTs) are in gold, and NGFs are in blue, with novel exons colored red. cDNA sequences recently deposited in GenBank (post 1/1/05) and ignored in evaluating novelty are shown in purple. This cluster of NGFs contributes 24 novel exons to a gene that spans >450 kb and consists of an estimated 66 exons. This gene appears to code for a novel axonemal dynein heavy-chain polypeptide.

This Article

  1. Genome Res. 17: 1763-1773

Preprint Server