Figure 1.
Condition-dependent annotation (CDA). A schematic representation of the CDA as a set of associations between genes and processes under various conditions. The basic element is a table specifying an association between genes and processes. This condition-dependent association table is the content of each entry of the CDA. These entries are spanned in turn by two dimensions representing growth media and the availability of oxygen (but additional dimensions can be added in principle in accordance with the data available). We consider two annotation systems, for single- and for double-knockouts simulations.
