Figure 4.
Reduced RNA level of the ADAR family is detected in human brain tumors. Real-time PCR analysis was performed in order to quantify the relative RNA levels of ADAR, ADARB1, and ADARB2 in normal and in different grades and types (according to WHO classification) of brain tumors. Values were normalized using S12, and the ΔΔCt method was applied. The y axis represents the relative ADARs expression level of (A) ADAR, (B) ADARB1, and (C) ADARB2. Error bars represent SEM. LGA, low-grade astrocytomas; AA, anaplastic astrocytomas; GBM, glioblastomas multiforme; Oligo, oligodendrogliomas.
