A comprehensive ChIP–chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members

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Figure 9.
Figure 9.

Categorizing the universe of promoters that bind E2F. Combining the lists of highly enriched (>1.0 on the array) promoters from one array from each of the 15 conditions (3 E2Fs × 5 cell types), we found a total of exactly 8000 unique promoters. Then, we classified each promoter into the displayed categories. Almost half of the 8000 promoters were found in multiple cell types and were bound by multiple E2Fs. A large fraction of the 1 E2F in 1 Cell Type category is comprised of promoters that were only found as Ntera2 E2F6 promoters, consistent with pairwise promoter array analyses across E2Fs and cell types (see Figs. 3 and 4).

This Article

  1. Genome Res. 17: 1550-1561

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