Prediction of individual genetic risk to disease from genome-wide association studies

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Table 1.

Summary statistics for the risk allele models

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Table 1.

The mean and maximum relative risk (RR) of simulated disease risk loci, percentage of the genetic variance explained by the locus with the largest individual variance (PVG1), percentage of genetic variance explained by variants with risk minor allele frequency <0.10 (PVGMAF10), and percentage of genetic variance explained by variants with risk minor allele frequency <0.05 (PVGMAF05) are shown. Mean of 10,000 simulation replicates.

This Article

  1. Genome Res. 17: 1520-1528

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