Prediction of individual genetic risk to disease from genome-wide association studies

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Relative risk of disease for the estimated top 5% of individuals at risk of a new sample of 1000 people following a case-control study with sample size of N each of cases and controls. A CDCV disease model is assumed with population prevalence (K) and heritability (h2) of the disease. Results for the neutral model were similar. Mean of 100 simulation replicates. The legend lists the data series in their order at 1000 risk loci.

This Article

  1. Published in Advance September 4, 2007, doi: 10.1101/gr.6665407 Genome Res. 17: 1520-1528

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research