
Sites under positive and negative selection in ora coding sequences. A schematic representation of site-by-site selective pressure is shown on ora receptor sequences drawn based on the edited nucleotide alignment, which was generated from the corresponding amino acid alignment used for Fig. 3. SLAC analysis shows the probability of sites being under selective pressure (negative selection in light blue (P < 0.2) or blue (P < 0.1), neutral selection in gray, positive selection not observed even at P < 0.2 level. All orthologs of each gene were used for this analysis; the results for three genes are shown: (A) ora1, (B) ora2, (C) ora4.











