Figure 1.
The position weight matrix and the sequence logo of the cartilage-specific SOX-binding profile constructed from experimentally validated SOX sites. Thirty-one experimentally validated SOX-binding sites from three genes were collected from the literature and used to model a SOX-binding profile for searching the cartilage gene set. (A) An illustration of the position weight matrix developed using these sites. (B) The sequence logo describing the position weight matrix (Schneider and Stephens 1990). For sequences and species information, see Supplemental Table 1.
