Overexpression of genes on the X chromosome in mid-late pachytene spermatocytes of sterile males. (a) Percentage of overexpressed genes in individual chromosomes of sterile B10-T43/+ males compared to fertile controls (B10 and B10-T43/T43). Significant enrichment of overexpressed genes (P < 0.05) was found on chromosome X (red) at mid-late pachytene (P ≤ 0.00017; one-tailed Fisher exact tests). (b) Distribution of expression changes between the sterile and fertile males along the X chromosome. These changes were calculated as in Figure 2. Significant expression differences are plotted in green (P < 0.05) and red (P < 0.01). Only the genes expressed in the specified cell population from males of at least one genotype are shown.
