Comparative analysis of each C. perfringens genome. (A) ATCC 13124; (B) SM101; (C) Strain 13. For each genome, data are from outermost circle to innermost. (Circles 1 and 2) Tick marks represent predicted coding sequences on the plus strand (circle 1) and minus strand (circle 2) colored by cellular role. Role categories and colors are as follows: amino acid biosynthesis, violet; biosynthesis of cofactors, prosthetic groups and carriers, light blue; cell envelope, light green; cellular processes, red; central intermediary metabolism, brown; DNA metabolism, gold; energy metabolism, light gray; fatty acid and phospholipid metabolism, magenta; protein synthesis and fate, pink; biosynthesis of purines, pyrimidines, nucleosides, and nucleotides, orange; regulatory functions and signal transduction, olive; transcription, dark green; transport and binding proteins, blue–green; other categories, salmon; unknown function, gray; conserved hypothetical proteins, blue; hypothetical proteins, black. (Circles 3 [blue] and 4 [red]) Genes identified by MUMmer analysis to be present in one genome but absent at that position in one other genome: (A) Circle 3: present in ATCC 13124 and absent in Strain 13; Circle 4: present in ATCC 13124 and absent in SM101. (B) Circle 3: present in SM101 but absent in Strain 13; Circle 4: present in SM101 but absent in ATCC 13124. (C) Circle 3: present in Strain 13 but absent in ATCC 13124; Circle 4: present in Strain 13 but absent in SM101. Circle 5: Phage genes (green), capsule-associated genes (purple) and IS elements (black). Circle 6: %G+C. Circle 7: χ2of trinucleotide composition.
