
Figure 1.
Schematic of ubiquitin-targeting system. The top panel shows the SCF1 (Cullin1) complex, which uses Skp-related and F-box proteins as substrate adapters. The domain marked “FTH etc.” varies depending on the specific adapter. The bottom panel shows the SCF3 (Cullin3) complex, which uses BTB proteins as substrate adapters. The domain marked “MATH etc.” varies depending on the specific adapter. (Ub) Ubiquitin.











