Suz12 binds to silenced regions of the genome in a cell-type-specific manner

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Figure 2.
Figure 2.

Suz12 target genes are cell type specific. Shown are the categories of Suz12 target genes, as determined using the program DAVID, for (A) the 1076 set of F9 Suz12 targets, (B) the top 1000 Suz12 targets in mES cells, (C) the top 600 SUZ12 targets from Ntera2 cells, (D) the top 600 SUZ12 targets from SW480 cells, (E) the top 600 SUZ12 targets from MCF7 cells, and (F) a set of 1000 randomly chosen promoters. Shown in parentheses are the P-values, which indicate the probability that the category has been identified by random chance. The black bars indicate Suz12 target genes that are stem cell or germ cell tumor specific, the hatched bars indicate Suz12 target genes that are common to all cell types, and the open bars indicate the most common categories of genes in a randomly chosen set of 1000 promoters.

This Article

  1. Genome Res. 16: 890-900

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