Functional noncoding sequences derived from SINEs in the mammalian genome

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Figure 3.
Figure 3.

Chimeric structure of 5S rRNA and tRNA-derived DeuSINEs. (A) Comparison of the tRNA-derived regions of LmeSINE1a and LmeSINE1b with a part of the 5S rRNA-derived SINEs, AmnSINE1, SINE3, SINE3_IP, and OS-SINE1. Box A and Box B are the pol III promoter sequences of the two LmeSINEs. (B) A possible scheme for the structural evolution of the 5S rRNA-derived SINE families. The green boxes and the blue boxes denote the Deu-domain and 3′-tail, respectively. A 5S rRNA sequence (red boxes) became joined with a tRNA-derived SINE, with subsequent partial deletion of the original tRNA-derived promoter region (yellow boxes).

This Article

  1. Genome Res. 16: 864-874

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